Medchemexpress LLC Aβ/tau aggregation-IN-1 | 2252162-81-3 | 98.1% | C25H21IN2O | 100 MG

Supplier:  Medchemexpress LLC HY141661100MG

Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ1-42 β-sheets formation and tau aggregation. It has KD values of 160 μM with Aβ1-42 and 337 μM with tau. This compound can permeate the blood-brain barrier. It significantly declines tau aggregation foci, effectively inhibiting Aβ1-42 aggregation by 84.7%-99.5% and tau aggregation by 71.2%-101.8%.

• Inhibits Aβ1-42 β-sheets formation
• Inhibits tau aggregation
• Permeates the blood-brain barrier
• Declines tau aggregation foci
• Inhibits self-induced Aβ1-42 aggregation
• Shows binding abilities with Aβ1-42 and tau

Catalog No. 50-003-54101