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Cayman Chemical -a-Tocopherol Acetate 25g
SDP

Supplier:  Cayman Chemical 3179525 G

Encompass_Preferred

A BET family protein inhibitor binds to BD1 in BRD2 BRD3 BRD4 and BRDT (Kds 1.6 2.1 1.7 and 5 nM respectively) as well as BD2 (Kds 5.9 6.2 6.1 and 120 nM respectively) binds to bromodomains of CBP and p300 (Kds ~100 nM for both) inhibits CpG-induced proliferation of primary CLL cells from 0.1-10 UM inhibits Ba/F3 cell-induced splenomegaly in mice from 0.5-10 mg/kg reduces tumor volume and increases survival in YUMM3.3 and D4M3.A mouse syngeneic B-RAFV600E mutant melanoma models

Catalog No. 50-294-6365


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