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ABclonal Technology A0062-500ul CYP1A2
Supplier: ABclonal Technology A0062500UL
This gene encodes a member of the cytochrome P450 superfamily of enzymes The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs) some of which are found in cigarette smoke The enzymes endogenous substrate is unknown however it is able to metabolize some PAHs to carcinogenic intermediates Other xenobiotic substrates for this enzyme include caffeine aflatoxin B1 and acetaminophen The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3 untranslated region
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