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ABclonal Technology LIMK1 Rabbit pAb
SDP

Supplier:  ABclonal Technology A166641000UL

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LIM proteins, including LIM kinase-1 (LIMK1), contain LIM domains with two zinc fingers, likely mediating protein-protein interactions. LIMK1, part of a subfamily with two LIM motifs and a kinase domain, is a serine/threonine kinase that regulates actin polymerization by phosphorylating and inactivating cofilin. It is widely expressed during development and plays a role in cytoskeletal structure, axon growth, and brain development. LIMK1 hemizygosity is linked to impaired visuospatial cognition in Williams syndrome. Alternative splicing produces multiple isoforms of this protein.

Catalog No. 50-001-11332


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