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ABclonal Technology A16664-1000ul LIMK1
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Supplier:  ABclonal Technology A166641000UL

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LIM proteins including LIM kinase-1 (LIMK1) contain LIM domains with two zinc fingers likely mediating protein-protein interactions LIMK1 part of a subfamily with two LIM motifs and a kinase domain is a serine/threonine kinase that regulates actin polymerization by phosphorylating and inactivating cofilin It is widely expressed during development and plays a role in cytoskeletal structure axon growth and brain development LIMK1 hemizygosity is linked to impaired visuospatial cognition in Williams syndrome Alternative splicing produces multiple isoforms of this protein

Catalog No. 50-001-11332


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