Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Unclassified Organic Compounds
  6. 916714100MG

Sigma Aldrich A1V2Pf2-Nhet

Catalog No. 916714100MG Shop All MilliporeSigma Sigma Organic Chemistry Products
Encompass
Change view
Click to view available options
Quantity:
50 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
91-671-4100MG 50 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 91-671-4100MG Supplier Sigma Aldrich Supplier No. 916714100MG
Only null left
Add to Cart
Add to Cart

Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

A1V2PF2-NHEt is an in silico-derived inhibitor of apoptosis protein (IAP)-recruiting ligand for targeted protein degradatio and SNIPER (specific and non-genetic IAP-dependent protein erasers) development, launched in partnership with ComInnex. Learn more about the novel IAP ligands generated through virtual screening of AVP mimetics in our Technology Spotlight. An N-terminal variant of A1V2PF2-NHEt is also available as BocA1V2PF2 (917974).A1V2PF2-NHEt conjugates are also available for degrader synthesis. Browse our full synthesis offering here for streamlining SNIPER and PROTAC™ degrader libraries: Degrader Building Blocks917931 A1V2PF2-NHEt-C6-NH2916684 A1V2PF2-NHEt-C10-NH2916935 A1V2PF2-NHEt-PEG1-NH2917192 A1V2PF2-NHEt-PEG3-NH2Technology Spotlight: Degrader Building Blocks with Inhibitor of Apoptosis Protein (IAP) In Silico-Derived LigandsIn Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)SNIPERs-Hijacking IAP activity to induce protein degradationE3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New OnesPROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Specifications

CAS 390040-83-0
Linear Formula C20H25N3O2
Quantity 50 mg
Synonym tert-Butyl (17-(4-(4-(N-Benzyl-2-chloroacetamido)phenoxy)phenoxy)-3,6,9,12,15-pentaoxaheptadecyl)carbamate; Crosslinker-E3 Ligase ligand conjugate; Protein degrader building block for PROTAC(R) research; RNF4-targeting building block; Template for synthesis of targeted protein degrader
Molecular Weight (g/mol) 731.27 g/mol
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.