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A23187, 98%, free acid, Thermo Scientific Chemicals

Catalog No. AC328080050
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Quantity:
1 mg
5 mg
Packaging:
Glass Bottle
Glass Bottle in Plastic Container

A23187 (Calcimycin), CAS # 52665-69-7, is a calcium ionophore-based antibiotic.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description


• A23187 is a polyether substance that permeabilizes cell membranes to calcium and other divalent cations


Applications
• A23187 can be used for the study of mitochondrial physiology because it acts as an uncoupling agent
• A23187 can be used to study the roles of divalent cations in cell physiology
• When bound to fluorescent calcium ions, A23187 can be useful for imaging studies

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 52665-69-7
Molecular Formula C29H37N3O6
Molecular Weight (g/mol) 523.63
MDL Number MFCD00151202,MFCD00151202
InChI Key HIYAVKIYRIFSCZ-CVXKHCKVSA-N
PubChem CID 97043288
IUPAC Name 5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid
SMILES CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O

Specifications

Physical Form Solid
CAS Min % 97.5
Melting Point 182.0°C to 193.0°C
CAS Max % 100.0
Infrared Spectrum Authentic
Packaging Glass Bottle
Color White
Quantity 5 mg
Assay Percent Range 98%
Merck Index 15, 1642
Solubility Information Solubility in water: .. Other solubilities: soluble in dmso, ethylacetate, methanol, ethanol
Formula Weight 523.63
Percent Purity 98%
Chemical Name or Material A23187, Free acid
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Hazard Category GHS Signal Word: Warning
Hazard Statement GHS H Statement:
Harmful in contact with skin.
Harmful if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Harmful if swallowed.
Causes serious eye irritation.
Precautionary Statement GHS P Statement:
IF ON SKIN: Wash with plenty of soap and water.
Wear protective gloves/protective clothing/eye protection/face protection.
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

RUO – Research Use Only

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