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Enzo Life Sciences A771726 (25mg). CAS: 108605-62-5
SDP

Supplier:  Enzo Life Sciences ALX430096M025

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Physiologically active metabolite of the immunosuppressive drug leflunomide (ALX-430-095). Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-κB activation in a dose- and time-dependent manner. Also inhibits the activity of cyclooxygenase-2 (COX-2) in vitro and in vivo. Alternative name: N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide. Purity: ≥98% (HPLC). Appearance: White solid. Solubility: Soluble in DMSO. Long Term Storage: +4°C.

Catalog No. 50-200-9200


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