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Medchemexpress LLC AAPK-25 | 2247919-28-2 | 98.1% | 442.32 g·mol⁻1 | C21H13Cl2N3O2S | 25MG
SDP

Supplier:  Medchemexpress LLC HY12624925MG

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AAPK-25 is a small-molecule dual inhibitor of Aurora kinases and Polo-like kinases (PLKs) used for research into cell-cycle regulation and anti-tumor mechanisms. It induces mitotic delay and prometaphase arrest, increases histone H3 (Ser10) phosphorylation, and promotes apoptosis in responsive cell models.

  • Dual Aurora and PLK inhibition with nanomolar affinity.
  • Induces mitotic delay and prometaphase arrest.
  • Validated in cell-based assays for apoptosis induction.
  • Available as solid and DMSO solution formats for flexible use.
  • Characterized chemical identity with confirmed purity and formula.

Catalog No. 50-002-34970


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