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Amsbio LLC Ab Heparan Sulfate, BIOTINYLATED (LOW BIOTIN) clone F58-10E4, 50ug pack
Supplier: Amsbio LLC 370255B50L
Biotinylated antibodies offer advantages in several key applications, by cutting out the need for the use of conjugated secondary antibodies to quantify the level of detection/binding in immunological assays. The antibody (F58-10E4 clone) reacts with the 10E4 epitope, which is present in many types of heparan sulfate. 10E4 epitope includes (an) N-sulfated glucosamine residue(s) that are critical for the reactivity of the F58-10E4 antibody. The reactivity of the antibody with most heparan sulfates is nearly completely abolished after treatment of the glycosaminoglycan with bacterial heparatinase I (Heparinase III) from Flavobacterium heparinum (EC 4.2.2.8). The 10E4 antibody does not react with hyaluronan, chondroitin sulfate, dermatan sulfate, keratan sulfate or DNA. Host species: Mouse, Isotype: IgM, Label/Conjugate: Biotin, Species reactivity: Broad, Storage: 2 - 8 deg C.
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