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Cayman Chemical AbacavIrsulfate 50mg
Supplier: Cayman Chemical 1474650 MG
A nucleoside analog and HIV-1 reverse transcriptase inhibitor (Ki = 2.1 µM for the wild-type enzyme); inhibits replication of a variety of HIV-1 and HIV-2 strains, including strains resistant to zidovudine or didanosine in HeLa cells stably expressing CD4 (IC50s = 5.8-21 µM); inhibits replication of eight HIV-1 clinical isolates in phytohemagglutinin-stimulated isolated human peripheral blood lymphocytes (mean IC50 = 0.26 µM); inhibits HBV DNA synthesis in HepG2 cells (IC50 = 7 µM) and is also active against human cytomegalovirus (CMV) strain AD169 and the Petaluma strain of FIV in plaque reduction assays (IC50s = 32 and 0.4 µM, respectively)
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