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Cayman Chemical AbaloparatIdeacetate 10mg
SDP

Catalog No. 502937206
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A synthetic derivative of PTHrP (1-34) and an agonist of PTH1R; selectively binds to the RG over the R0 conformation of PTHrP; induces cAMP signaling more transiently than PTH (1-34), PTHrP (1-36), or LA-PTH (EC50s = 0.08, 0.44, 0.46, and 0.21 nM, respectively); increases areal bone mineral density in the lumbar spine, total femur, and femur diaphysis in ovariectomized osteopenic rats at 5 and 20 UG/kg per day for six weeks; increases the incidence of focal osteoblast hyperplasia, benign osteoblastoma, and osteosarcoma in rats in a time- and dose-dependent manner at ≥10 UG/kg per day for up to two years

Catalog No. 50-293-7206 Supplier Cayman Chemical Supplier No. 2881610 MG
May include imposed supplier surcharges.
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A synthetic derivative of PTHrP (1-34) and an agonist of PTH1R; selectively binds to the RG over the R0 conformation of PTHrP; induces cAMP signaling more transiently than PTH (1-34), PTHrP (1-36), or LA-PTH (EC50s = 0.08, 0.44, 0.46, and 0.21 nM, respectively); increases areal bone mineral density in the lumbar spine, total femur, and femur diaphysis in ovariectomized osteopenic rats at 5 and 20 UG/kg per day for six weeks; increases the incidence of focal osteoblast hyperplasia, benign osteoblastoma, and osteosarcoma in rats in a time- and dose-dependent manner at ≥10 UG/kg per day for up to two years

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