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Medchemexpress LLC Abatacept | 332348-12-6 | 99.01% | 84.4 kDa | 10 MG
SDP

Supplier:  Medchemexpress LLC HY108829A1MG

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Abatacept (powder) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation modulator and a protein agent for autoimmune diseases.

  • Reduces paw edema.
  • Exhibits linear pharmacokinetics (PK) across studied doses.
  • Reduces the proportion of activated T cells (CD44highCD62L-) and inhibits the up-regulation of ICOS and CD71 in homozygous DO11.10 RAG-2-/- BALB/c (H-2d/d) mice.

Catalog No. 50-003-44694


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