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Medchemexpress LLC ABBV-167 | 1351456-78-4 | 98.1% | C46H53ClN7O11PS | 1 ML
Supplier: Medchemexpress LLC HY14220910MM/1ML
ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax. It demonstrated a lower food effect compared to venetoclax tablets and extensively converts to venetoclax following oral administration. This product is for research use only and has not been fully validated for medical applications.
- Phosphate prodrug of BCL-2 inhibitor venetoclax
- Demonstrates lower food effect compared to venetoclax tablets
- Extensively converts to venetoclax after oral administration
- Molecular weight: 978.45
- Targets Bcl-2 family
- Involved in Apoptosis pathway
- Soluble in DMSO at 100 mg/mL (102.20 mM) with ultrasonication
- In vivo solubility of ≥ 2.5 mg/mL (2.56 mM) in 10% DMSO and 90% (20% SBE-β-CD in saline)
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