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Medchemexpress LLC ABD957 | 3007772-60-0 | 98.1% | C27H36F3N7O5S | 50 MG
Supplier: Medchemexpress LLC HY14216150MG
ABD957 is a potent and selective covalent inhibitor of the ABHD17 family of depalmitoylases. This compound can block N-Ras signaling and inhibit the growth of NRAS-mutant AML cells. It is intended for research use only.
- Potent and selective covalent inhibitor of ABHD17 family depalmitoylases
- Blocks N-Ras signaling
- Inhibits the growth of NRAS-mutant AML cells (OCI-AML3, THP1, HL60)
- Attenuates N-Ras depalmitoylation in AML cells at 500 nM
- Has an IC50 of 0.21 μM for ABHD17B
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