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Medchemexpress LLC Abemaciclib metabolite M18 | 2704316-81-2 | 98.0% | 1 ML
SDP

Catalog No. 5000342241
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Abemaciclib metabolite M18 (LSN3106729), a metabolite of Abemaciclib, functions as a CDK inhibitor with antitumor activity. It can also be used with a CRBN ligand to engineer a PROTAC CDK4/6 degrader.

  • Functions as a CDK inhibitor.
  • Exhibits antitumor activity.
  • Used with a CRBN ligand to design a PROTAC CDK4/6 degrader.
  • Targets CDK4 and CDK6.
  • Inhibits retinoblastoma (RB) protein phosphorylation, inducing cell cycle arrest.
  • Promotes T-cell persistence and increased immunologic memory in mice.

Catalog No. 50-003-42241 Supplier Medchemexpress LLC Supplier No. HY126534A10MM/1ML
May include imposed supplier surcharges.
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Abemaciclib metabolite M18 (LSN3106729), a metabolite of Abemaciclib, functions as a CDK inhibitor with antitumor activity. It can also be used with a CRBN ligand to engineer a PROTAC CDK4/6 degrader.

  • Functions as a CDK inhibitor.
  • Exhibits antitumor activity.
  • Used with a CRBN ligand to design a PROTAC CDK4/6 degrader.
  • Targets CDK4 and CDK6.
  • Inhibits retinoblastoma (RB) protein phosphorylation, inducing cell cycle arrest.
  • Promotes T-cell persistence and increased immunologic memory in mice.

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