Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Abemaciclib metabolite M18 | 2704316-81-2 | 98.0% | 1 ML
Supplier: Medchemexpress LLC HY126534A10MM/1ML
Abemaciclib metabolite M18 (LSN3106729), a metabolite of Abemaciclib, functions as a CDK inhibitor with antitumor activity. It can also be used with a CRBN ligand to engineer a PROTAC CDK4/6 degrader.
- Functions as a CDK inhibitor.
- Exhibits antitumor activity.
- Used with a CRBN ligand to design a PROTAC CDK4/6 degrader.
- Targets CDK4 and CDK6.
- Inhibits retinoblastoma (RB) protein phosphorylation, inducing cell cycle arrest.
- Promotes T-cell persistence and increased immunologic memory in mice.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?