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Medchemexpress LLC Abemaciclib metabolite M18 (hydrochloride) | 2704316-82-3 | 98.2% | 50 MG
Supplier: Medchemexpress LLC HY126534A50MG
Abemaciclib metabolite M18 hydrochloride is a metabolite of Abemaciclib and functions as a CDK inhibitor with antitumor activity. It has been used to design PROTAC CDK4/6 degraders. This product is for research use only, suitable for laboratory chemical applications and experienced personnel. It inhibits retinoblastoma (RB) protein phosphorylation, inducing cell cycle arrest, and can increase T-cell persistence and immunologic memory.
- Solid appearance
- Purity of 98.18%
- Molecular weight: 531.00
- Chemical formula: C25H29ClF2N8O
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
- Acts as a CDK inhibitor
- Exhibits antitumor activity
- Inhibits retinoblastoma (RB) protein phosphorylation
- Induces cell cycle arrest
- Can be used to design PROTAC CDK4/6 degrader
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