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Medchemexpress LLC Abemaciclib metabolite M2 | 1231930-57-6 | 99.8% | 10 MG
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Catalog No. 5000342932
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Abemaciclib metabolite M2 is a potent CDK4 and CDK6 inhibitor, acting as a metabolite of Abemaciclib. It exhibits anti-cancer activity with IC50s of 1.2 nM for CDK4 and 1.3 nM for CDK6. This metabolite is the most prominent and active plasma metabolite found in humans. It shows plasma protein binding in rat, dog, and human between 83-92%.

  • Acts as a potent CDK4 and CDK6 inhibitor
  • Exhibits anti-cancer activity
  • Most prominent and active plasma metabolite in humans
  • Shows plasma protein binding in rat, dog, and human (83-92%)

Catalog No. 50-003-42932 Supplier Medchemexpress LLC Supplier No. HY12866910MG
May include imposed supplier surcharges.
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Abemaciclib metabolite M2 is a potent CDK4 and CDK6 inhibitor, acting as a metabolite of Abemaciclib. It exhibits anti-cancer activity with IC50s of 1.2 nM for CDK4 and 1.3 nM for CDK6. This metabolite is the most prominent and active plasma metabolite found in humans. It shows plasma protein binding in rat, dog, and human between 83-92%.

  • Acts as a potent CDK4 and CDK6 inhibitor
  • Exhibits anti-cancer activity
  • Most prominent and active plasma metabolite in humans
  • Shows plasma protein binding in rat, dog, and human (83-92%)

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