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Medchemexpress LLC Abemaciclib metabolite M20 | 2138499-06-4 | 98.2% | 100 MG
SDP

Catalog No. 5000340021
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Abemaciclib metabolite M20 (LSN3106726) is the active metabolite of Abemaciclib and a selective CDK4/6 inhibitor for the treatment of cancer. It induces senescence in breast cancer cells at concentrations of 200 nM and 500 nM over 6-8 days.

  • Induces senescence in breast cancer cells.
  • Inhibits the growth and cell cycle progression of non-small cell lung cancer (NSCLC) cells, colorectal cancer (CRC) cells, and breast cancer cells.
  • IC50 value for CDK4 and CDK6 is in the range of 1-3 nM.

Catalog No. 50-003-40021 Supplier Medchemexpress LLC Supplier No. HY129336100MG
May include imposed supplier surcharges.
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Abemaciclib metabolite M20 (LSN3106726) is the active metabolite of Abemaciclib and a selective CDK4/6 inhibitor for the treatment of cancer. It induces senescence in breast cancer cells at concentrations of 200 nM and 500 nM over 6-8 days.

  • Induces senescence in breast cancer cells.
  • Inhibits the growth and cell cycle progression of non-small cell lung cancer (NSCLC) cells, colorectal cancer (CRC) cells, and breast cancer cells.
  • IC50 value for CDK4 and CDK6 is in the range of 1-3 nM.

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