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Cayman Chemical AbIetIc AcId 25g
Supplier: Cayman Chemical 2492725 G
A diterpene with enzyme inhibitory, antiproliferative, antibacterial, and anti-obesity biological properties; inhibits soybean 5-LO and rat prostate testosterone 5α-reductase in cell-free assays (IC50s = 29.5 and 56 μM, respectively); selectively inhibits proliferation of HeLa cervical cancer cells over noncancerous Vero cells (IC50s = 15 and 53 μM, respectively); inhibits growth of S. epidermidis, P. acnes, and S. mitis bacteria (MICs = 8, 4, and 16 μg/ml, respectively); induces FABP2 and LPL expression in differentiated 3T3-L1 mouse adipocytes at 25 μM; decreases body and adipose tissue weight in mice fed a high-fat diet at 40 mg/kg per day
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