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Medchemexpress LLC Abietic acid | 514-10-3 | 25 MG
Supplier: Medchemexpress LLC 25MGHYN6871
Abietic acid is an orally active diterpene isolated from Colophony. It exhibits anti-proliferative, anti-inflammatory, anti-obesity, bacteriostatic, cell cycle arresting, and pro-apoptotic activities. It is promising for research in non-small-cell lung cancer (NSCLC), liver injury-related diseases, and psoriasis.
- Inhibits lipoxygenase activity for allergy.
- Enhances cell migration and tube formation in HUVECs.
- Induces angiogenic potential through upregulation of extracellular signal-regulated kinase (ERK) and p38 expression.
- Attenuates sepsis-induced lung injury by inhibiting the NF-κB pathway to inhibit M1 macrophage polarization.
- Exhibits a positive effect against liver injury by attenuating inflammation and ferroptosis.
- Significantly reduces the proliferation and growth of NSCLC cells by IKKβ inhibition.
- Ameliorates psoriasis-like inflammation and modulates gut microbiota in mice.
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