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Apexbio Technology LLC Abietic acid 514-10-3 5mg
Supplier: Apexbio Technology LLC A15035
Abietic acid (CAS 514-10-3) is a small-molecule inhibitor targeting IKK and lipoxygenase It is designed to inhibit these enzymes thereby modulating NF- B signaling and inflammatory pathways Abietic acid exerts its biological activity primarily through inhibition of lipoxygenase activity and suppression of NF- B signaling pathways including the blockade of IKK In cell-based studies abietic acid demonstrates cytostatic activity with an IC50 of approximately 20 M in human lung cancer cell lines Based on these pharmacological properties abietic acid holds research potential in inflammation human cancer psoriasis sepsis-associated lung injury and non-small cell lung carcinoma
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