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Cayman Chemical AbIrateron Acetate 50mg
Supplier: Cayman Chemical 1514850 MG
A CYP17A1 inhibitor (IC50s = 17 and 18 nM for inhibition of C17,20-lyase and 17α-hydroxylase activities, respectively); prodrug form of abiraterone; reduces plasma testosterone levels, increases plasma luteinizing hormone levels, and reduces ventral prostate, seminal vesicle, testis, and kidney weight in mice at 0.1 and 0.5 mmol/kg per day; reduces SARS-CoV-2 viral load in the culture supernatant of infected Vero E6 cells (EC90 = 8.4 μM) and is active in a plaque reduction assay (EC50 = 1.94 μM)
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