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Medchemexpress LLC Abiraterone acetate | 154229-18-2 | 99.91% | C26H33NO2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY750545MG

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Abiraterone acetate is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. It is a proagent form of Abiraterone.

  • Oral administration
  • Potent, selective, and irreversible inhibitor of CYP17A1
  • Exhibits antiandrogen activity
  • Prodrug form of Abiraterone
  • Inhibits 17,20-lyase and 17α-hydroxylase activity
  • Inhibits proliferation of AR-positive prostate cancer cell lines
  • Blocks synthesis of 5α-dione and DHT
  • Inhibits CRPC progression
  • Prolongs survival in castration-resistant prostate cancer (CRPC)
  • Inhibits dehydroepiandrosterone (DHEA) depletion and Δ4-androstenedione (AD) accumulation

Catalog No. 50-004-33711


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