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Eurofins Discoverx Abl (T315I), active, 250 µg. (14-522M)
Supplier: Eurofins Discoverx 14522M
N-terminal 6xHis-tagged recombinant, human Abl, amino acids 27-end containing the T315I mutation. Contains the gatekeeper mutation T315I in the ATP-binding domain. This mutation decreases the sensitivity to Gleevec by more than 200-fold as compared to the wild type sequence. For detailed product information, visit www.discoverx.com/proteins.
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