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Apexbio Technology LLC ABT-263 (Navitoclax) 923564-51-6 10mM (in 1mL DMSO)
SDP

Catalog No. 5000062945
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ABT-263 (Navitoclax CAS 923564-51-6) is an orally bioavailable small molecule inhibitor targeting anti-apoptotic proteins of the Bcl-2 family including Bcl-2 Bcl-xl and Bcl-w By disrupting interactions between these anti-apoptotic factors and pro-apoptotic proteins (Bim Bad Bak) ABT-263 promotes activation of caspase-dependent apoptotic pathways resulting in programmed cell death This compound is utilized extensively in oncology research to explore apoptotic mechanisms and evaluate antitumor efficacy in various cancer models

Catalog No. 50-000-62945 Supplier Apexbio Technology LLC Supplier No. A30075.1
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ABT-263 (Navitoclax CAS 923564-51-6) is an orally bioavailable small molecule inhibitor targeting anti-apoptotic proteins of the Bcl-2 family including Bcl-2 Bcl-xl and Bcl-w By disrupting interactions between these anti-apoptotic factors and pro-apoptotic proteins (Bim Bad Bak) ABT-263 promotes activation of caspase-dependent apoptotic pathways resulting in programmed cell death This compound is utilized extensively in oncology research to explore apoptotic mechanisms and evaluate antitumor efficacy in various cancer models

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