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Apexbio Technology LLC ABT-263 (Navitoclax) 923564-51-6 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A30075.1
ABT-263 (Navitoclax CAS 923564-51-6) is an orally bioavailable small molecule inhibitor targeting anti-apoptotic proteins of the Bcl-2 family including Bcl-2 Bcl-xl and Bcl-w By disrupting interactions between these anti-apoptotic factors and pro-apoptotic proteins (Bim Bad Bak) ABT-263 promotes activation of caspase-dependent apoptotic pathways resulting in programmed cell death This compound is utilized extensively in oncology research to explore apoptotic mechanisms and evaluate antitumor efficacy in various cancer models
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