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  8. ABT 751, Tocris Bioscience™

ABT 751, Tocris Bioscience™

Catalog No. 413810
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Catalog No. Quantity
41-381-0 10 mg
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Catalog No. 41-381-0 Supplier R&D Systems Supplier No. 4138/10
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Description

Inhibitor of microtubule polymerization; antimitotic and antitumor

Antimitotic agent, inhibits microtubule polymerization. Binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis. Exhibits antitumor activity. Also displays activity in cell lines resistant to vincristine, doxorubicin and cisplatin. Orally bioavailable.

Chemical Identifiers

CAS 141430-65-1
Molecular Formula C18H17N3O4S
Molecular Weight (g/mol) 371.411
InChI Key URCVCIZFVQDVPM-UHFFFAOYSA-N
Synonym unii-wdt5v5ob9f, wdt5v5ob9f, chembl20684, n-2-4-hydroxyphenyl amino-3-pyridyl-4-methoxybenzenesulfonamide, n-2-4-hydroxyphenyl amino-3-pyridinyl-4-methoxybenzenesulfonamide, n-2-4-hydroxyphenyl amino pyridin-3-yl-4-methoxybenzenesulfonamide, benzenesulfonamide,n-2-4-hydroxyphenyl amino-3-pyridinyl-4-methoxy, n-2-4-hydroxyphenylamino pyridin-3-yl-4-methoxybenzenesulfonamide, benzenesulfonamide, n-2-4-hydroxyphenyl amino-3-pyridinyl-4-methoxy
PubChem CID 3035714
IUPAC Name N-[2-(4-hydroxyanilino)pyridin-3-yl]-4-methoxybenzenesulfonamide
SMILES COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O

Specifications

Quantity 10 mg
Formula Weight 371.41
Percent Purity >98%
Chemical Name or Material ABT 751

Safety and Handling

Recommended Storage Store at +4°C
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