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Medchemexpress LLC AC-186 | 1421854-16-1 | 99.61% | 306.32 | 1 ML
SDP

Catalog No. 5000344017
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AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50 values of 6 nM for ERβ and 5000 nM for ERα. This compound has demonstrated gender-selective neuroprotective effects in a male rat model of Parkinson's disease by preventing motor, cognitive, and sensorimotor gating deficits and mitigating the loss of dopamine neurons in the substantia nigra. It also inhibits the growth of LNCaP cells.

  • Selective non-steroidal estrogen receptor β agonist
  • Demonstrates gender-selective neuroprotective effects
  • Inhibits growth of LNCaP cells in vitro
  • Suitable for research use only

Catalog No. 50-003-44017 Supplier Medchemexpress LLC Supplier No. HY11015710MM/1ML
May include imposed supplier surcharges.
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AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50 values of 6 nM for ERβ and 5000 nM for ERα. This compound has demonstrated gender-selective neuroprotective effects in a male rat model of Parkinson's disease by preventing motor, cognitive, and sensorimotor gating deficits and mitigating the loss of dopamine neurons in the substantia nigra. It also inhibits the growth of LNCaP cells.

  • Selective non-steroidal estrogen receptor β agonist
  • Demonstrates gender-selective neuroprotective effects
  • Inhibits growth of LNCaP cells in vitro
  • Suitable for research use only

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