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Cayman Chemical AC 187trIfluoROCTAte salt 10mg
Supplier: Cayman Chemical 3583910 MG
An antagonist of calcitonin and amylin receptors; inhibits human calcitonin-induced cAMP accumulation in COS-7 cells expressing the human calcitonin receptor, AMY1a, or AMY3a (pKBs = 7.15, 7.3, and 7.37, respectively); protects against Aβ42-induced apoptosis in primary rat basal forebrain neurons at 10 µM; intrathecal administration increases the paw withdrawal threshold in the von Frey test in a rat model of chronic peripheral neuropathic pain induced by spared nerve injury; reverses sCT-induced decreases in food intake in food-deprived rats at 10 UG/kg
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