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Medchemexpress LLC AC-55541 | 916170-19-9 | 99.4% | C25H20BrN5O3 | 100 MG
SDP

Catalog No. 5000354254
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AC-55541 is a highly selective agonist for protease-activated receptor 2 (PAR2), demonstrating a pEC50 of 6.7. It does not show activity at other PAR subtypes or at over 30 additional receptors associated with nociception and inflammation. AC-55541 has pEC50 values of 5.9 and 6.6 in PI hydrolysis assays and Ca2+ mobilization assays, and exhibits pronociceptive activity in vivo.

  • Highly selective agonist for PAR2 (pEC50=6.7)
  • No activity at other PAR subtypes or over 30 other receptors involved in nociception and inflammation
  • Purity 99.4%
  • Molecular weight 518.36
  • Appears as a white to off-white solid
  • Soluble in DMSO at ≥ 51 mg/mL
  • Suppresses poly I:C-induced CXCL10 mRNA in NHBE cells in vitro
  • Exhibits pronociceptive activity in vivo

Catalog No. 50-003-54254 Supplier Medchemexpress LLC Supplier No. HY14350100MG
May include imposed supplier surcharges.
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AC-55541 is a highly selective agonist for protease-activated receptor 2 (PAR2), demonstrating a pEC50 of 6.7. It does not show activity at other PAR subtypes or at over 30 additional receptors associated with nociception and inflammation. AC-55541 has pEC50 values of 5.9 and 6.6 in PI hydrolysis assays and Ca2+ mobilization assays, and exhibits pronociceptive activity in vivo.

  • Highly selective agonist for PAR2 (pEC50=6.7)
  • No activity at other PAR subtypes or over 30 other receptors involved in nociception and inflammation
  • Purity 99.4%
  • Molecular weight 518.36
  • Appears as a white to off-white solid
  • Soluble in DMSO at ≥ 51 mg/mL
  • Suppresses poly I:C-induced CXCL10 mRNA in NHBE cells in vitro
  • Exhibits pronociceptive activity in vivo

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