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Bachem Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

Supplier: Bachem 4026022.0005

Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid), 184179-08-6, C20H30N4O11, Mr 502.48, 5mg. Ac-DEVD-CHO. Ac-DEVD-CHO is a potent inhibitor of the poly(ADP-ribose) polymerase (PARP) cleavage by caspase-3 (IC50 = 0.2 nM). PARP cleavage occurs at the onset of apoptosis. The peptide aldehyde was able to attenuate apoptotic events in vitro (IC50 = 10 to 100 nM).
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