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Apexbio Technology LLC Ac-DEVD-pNA 189950-66-1 25mg
SDP

Catalog No. 5000061917
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Ac-DEVD-pNA (CAS 189950-66-1) is a chromogenic peptide substrate widely used for monitoring caspase-3 activity It consists of the tetrapeptide DEVD sequence an acetyl (Ac)-terminal modification and a para-nitroaniline (pNA) reporter moiety The sequence DEVD derives from the known caspase-3 cleavage site at Asp216 found in substrates such as poly(ADP-ribose) polymerase (PARP) Upon apoptosis activated caspase-3 recognizes and cleaves Ac-DEVD-pNA releasing free pNA detectable spectrophotometrically at 405 nm Thus Ac-DEVD-pNA serves as an important tool for quantifying caspase-3 activity in apoptotic cell lysates

Catalog No. 50-000-61917 Supplier Apexbio Technology LLC Supplier No. A874425
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Ac-DEVD-pNA (CAS 189950-66-1) is a chromogenic peptide substrate widely used for monitoring caspase-3 activity It consists of the tetrapeptide DEVD sequence an acetyl (Ac)-terminal modification and a para-nitroaniline (pNA) reporter moiety The sequence DEVD derives from the known caspase-3 cleavage site at Asp216 found in substrates such as poly(ADP-ribose) polymerase (PARP) Upon apoptosis activated caspase-3 recognizes and cleaves Ac-DEVD-pNA releasing free pNA detectable spectrophotometrically at 405 nm Thus Ac-DEVD-pNA serves as an important tool for quantifying caspase-3 activity in apoptotic cell lysates

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