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Medchemexpress LLC Ac-Exatecan | 2922852-48-8 | 99.0% | C26H24FN3O5 | 1 ML
SDP

Catalog No. 5000433015
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Ac-Exatecan is an acetylation-modified Exatecan, which functions as a common toxin component in Antibody-Drug Conjugate (ADC) preparation. It acts as an inhibitor of DNA topoisomerase I, with an IC50 of 2.2 μM, and demonstrates antitumor activity. This compound can be utilized as an ADC payload and is effective against P-glycoprotein mediated multi-drug resistant cells.

  • Acetylation-modified Exatecan
  • Functions as a common toxin component in ADC preparation (ADC cytotoxin)
  • Inhibits DNA topoisomerase I (IC50 = 2.2 μM)
  • Exhibits antitumor activity
  • Can be utilized as a payload for ADC
  • Effective against P-glycoprotein mediated multi-drug resistant cells

Catalog No. 50-004-33015 Supplier Medchemexpress LLC Supplier No. HY7949010MM/1ML
May include imposed supplier surcharges.
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Ac-Exatecan is an acetylation-modified Exatecan, which functions as a common toxin component in Antibody-Drug Conjugate (ADC) preparation. It acts as an inhibitor of DNA topoisomerase I, with an IC50 of 2.2 μM, and demonstrates antitumor activity. This compound can be utilized as an ADC payload and is effective against P-glycoprotein mediated multi-drug resistant cells.

  • Acetylation-modified Exatecan
  • Functions as a common toxin component in ADC preparation (ADC cytotoxin)
  • Inhibits DNA topoisomerase I (IC50 = 2.2 μM)
  • Exhibits antitumor activity
  • Can be utilized as a payload for ADC
  • Effective against P-glycoprotein mediated multi-drug resistant cells

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