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Medchemexpress LLC Ac-Exatecan | 2922852-48-8 | 99.0% | C26H24FN3O5 | 100 MG
SDP

Catalog No. 5000432363
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Ac-Exatecan is an acetylation-modified Exatecan, functioning as a common toxin component in Antibody-drug Conjugate (ADC) preparation and an inhibitor of DNA topoisomerase I. It demonstrates antitumor activity and serves as an effective payload for ADCs, also showing efficacy against P-glycoprotein mediated multi-drug resistant cells.

  • Acetylation-modified Exatecan
  • Common toxin component in ADC preparation
  • Inhibitor of DNA topoisomerase I (IC50 = 2.2 μM)
  • Exhibits antitumor activity
  • Can be used as a payload for ADC
  • Effective against P-glycoprotein mediated multi-drug resistant cells

Catalog No. 50-004-32363 Supplier Medchemexpress LLC Supplier No. HY79490100MG
May include imposed supplier surcharges.
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Ac-Exatecan is an acetylation-modified Exatecan, functioning as a common toxin component in Antibody-drug Conjugate (ADC) preparation and an inhibitor of DNA topoisomerase I. It demonstrates antitumor activity and serves as an effective payload for ADCs, also showing efficacy against P-glycoprotein mediated multi-drug resistant cells.

  • Acetylation-modified Exatecan
  • Common toxin component in ADC preparation
  • Inhibitor of DNA topoisomerase I (IC50 = 2.2 μM)
  • Exhibits antitumor activity
  • Can be used as a payload for ADC
  • Effective against P-glycoprotein mediated multi-drug resistant cells

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