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Medchemexpress LLC Ac-Exatecan | 2922852-48-8 | 99.0% | C26H24FN3O5 | 25 MG
SDP

Catalog No. 5000358876
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Ac-Exatecan is an acetylation-modified Exatecan. Exatecan is a common toxin component used in antibody-drug conjugate (ADC) preparation, acting as an ADC cytotoxin and an inhibitor of DNA topoisomerase I with an IC50 of 2.2 μM. It exhibits antitumor activity and can be utilized as a payload for ADCs. Exatecan is also effective against P-glycoprotein mediated multi-drug resistant cells.

  • Acetylation-modified Exatecan
  • Common toxin component in antibody-drug conjugate (ADC) preparation
  • Functions as an ADC cytotoxin
  • Inhibits DNA topoisomerase I (IC50 = 2.2 μM)
  • Exhibits antitumor activity
  • Can be utilized as a payload for ADCs
  • Effective against P-glycoprotein mediated multi-drug resistant cells

Catalog No. 50-003-58876 Supplier Medchemexpress LLC Supplier No. 25MGHY79490
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Ac-Exatecan is an acetylation-modified Exatecan. Exatecan is a common toxin component used in antibody-drug conjugate (ADC) preparation, acting as an ADC cytotoxin and an inhibitor of DNA topoisomerase I with an IC50 of 2.2 μM. It exhibits antitumor activity and can be utilized as a payload for ADCs. Exatecan is also effective against P-glycoprotein mediated multi-drug resistant cells.

  • Acetylation-modified Exatecan
  • Common toxin component in antibody-drug conjugate (ADC) preparation
  • Functions as an ADC cytotoxin
  • Inhibits DNA topoisomerase I (IC50 = 2.2 μM)
  • Exhibits antitumor activity
  • Can be utilized as a payload for ADCs
  • Effective against P-glycoprotein mediated multi-drug resistant cells

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