Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Enzo Life Sciences Ac-Leu-Leu-Nle-al (25mg). CAS: 110044-82-1
Supplier: Enzo Life Sciences BMLP1200025
Cell-permeable, peptide aldehyde inhibitor of calpain I (Ki=190nM), calpain II (Ki=150nM), cathepsin L (Ki=0.5nM) and other neutral cysteine proteases. Inhibits cell cycle progression at G1/S and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation. Also stimulates HMG-CoA synthase transcription by inhibiting degradation of active SREBP-1 (sterol regulatory element-binding protein 1). Protects against neuronal damage caused by hypoxia and ischemia. Inhibits apoptosis in thymocytes and metamyelocytes. Prevents nitric oxide production by activated macrophages by interfering with the transcription of inducible nitric oxide synthase . Inhibits proteolytic degradation of IκBα and IκBß in RAW macrophages induced with LPS. It also prolong association of MHC class I molecules with the transporters associated with antigen processing. Alternative name: ALLN, Calpain inhibitor I, Ac-LL-norleucinal. Purity: ≥95% (HPLC). Solubility: Soluble in ethanol (5 mg/ml) or DMSO (10 mg/ml).
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?