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Medchemexpress LLC Ac-Phe-{Orn}-Pro-{dCha}-Trp-Arg (lactam bridge: Orn2-Arg6) | 219639-75-5 | MFCD07363866 | ≥98.0% | 896.09 g·mol⁻¹ | C47H65N11O7 | 25 MG
Supplier: Medchemexpress LLC HY10617825MG
PMX-53 is a synthetic peptidic antagonist of the complement C5a receptor (CD88) used in research to probe complement-mediated inflammation. It is orally active and inhibits C5a-induced neutrophil responses with a reported IC50 of ≈20 nM. The compound is supplied as a solid; molecular formula C47H65N11O7; molecular weight 896.09 g·mol⁻1; recommended storage at -20°C (in solvent: -80°C for long-term).
- Potent C5aR antagonist with low-nanomolar activity.
- Active in both in vitro and in vivo models.
- Peptidic structure suitable for mechanistic studies of complement signaling.
- Stable solid form with defined storage conditions.
- Available in small research pack sizes for experimental flexibility.
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