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Enzo Life Sciences Ac-VDVAD-AFC (10mg)
Supplier: Enzo Life Sciences ALX260112M010
Fluorogenic substrate for caspase-2; similar to Ac-VDVAD-AMC but the AFC fluorophore has a greater Stokes’ shift upon cleavage. VDVAD has been found to be a preferred cleavage site for caspase-2 (Ich-1L). Increases in Ac-VDVAD-AFC cleavage correlated with losses in procaspase-2 (conversion to active caspase-2) in human neuroblastoma lines induced to apoptosis with C2-ceramide and NO. Alternative name: Caspase 2 substrate (fluorogenic). Formula: C33H41F3N6O12. MW: 770.7. Purity: ≥98% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: -20°C. Handling: Warm up to room temperature before opening. Keep cool and dry.
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