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Medchemexpress LLC Ac-VLPE-FMK | 2679825-27-3 | C25H41FN4O7 | 5 MG
Supplier: Medchemexpress LLC HY1536145MG
Ac-VLPE-FMK is a tetrapeptidyl mono-fluoromethyl ketone that acts as an inhibitor for Cathepsin B (Cat-B) and Cathepsin L (Cat-L). It is useful in research pertaining to cancer aggressiveness. In vitro studies show that it significantly impacts the cleavage of the probe Ac-PLVQ-AMC by human recombinant CtsB and L. Additionally, it inhibits the generation of fluorescence from the cleavage of the substrate Ac-PLVQ-AMC in 769-p and A498 cells.
- Tetrapeptidyl mono-fluoromethyl ketone
- Inhibits Cathepsin B and Cathepsin L
- Useful in cancer aggressiveness research
- Impacts cleavage of Ac-PLVQ-AMC probe by CtsB and L
- Inhibits fluorescence generation from Ac-PLVQ-AMC substrate cleavage
- Influences renal cancer cell migration rate
- Influences cellular adhesion
- Influences colony formation
- Influences marker expression in renal cancer cells
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