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Bachem Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid)

Supplier: Bachem 4027878.0025
Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid), 189275-71-6, C28H33N7O9, Mr 611.61, 25mg. Ac-WEHD-CHO. Ac-WEHD-CHO, a very potent reversible inhibitor of caspase-1 (ICE). It bears the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM it belongs to the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.
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