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ABclonal Technology GAPDH Rabbit pAb
Supplier: ABclonal Technology AC0271000UL
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase family, known as a moonlighting protein due to its multiple distinct functions. It catalyzes an important step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate with NAD and inorganic phosphate. The protein also has uracil DNA glycosylase activity in the nucleus and antimicrobial properties against E. coli, P. aeruginosa, and C. albicans. Additionally, similar proteins in mice have been linked to regulating mRNA stability, nitrosylating nuclear proteins, and acting as a transferrin receptor on macrophage surfaces. Many pseudogenes related to this gene exist in the human genome. Alternative splicing generates multiple transcript variants.
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