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Medchemexpress LLC Acacetin | 480-44-4 | 284.26 | 50 MG

Supplier: Medchemexpress LLC HYN045150MG
Acacetin is an orally active flavonoid, 5,7-Dihydroxy-4'-methoxyflavone, isolated from Dendranthema morifolium. It acts as a PI3Kγ inhibitor, inducing cell cycle arrest, apoptosis, and autophagy in various cancer cells. This compound exhibits potent anti-cancer and anti-inflammatory activities, making it a promising candidate for pain-related disease research.
- Orally active flavonoid
- Derived from Dendranthema morifolium
- Docks in ATP binding pocket of PI3Kγ
- Causes cell cycle arrest in cancer cells
- Induces apoptosis and autophagy in cancer cells
- Potent anti-cancer activity
- Potent anti-inflammatory activity
- Potential for pain-related diseases research
- Suppresses microglial activation in neuroinflammation models
- Reduces neuronal cell death in ischemia models
- Decreases visceral and inflammatory nociception
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