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Medchemexpress LLC ACBI1 | 2375564-55-7 | 99.92% | 100 MG
SDP

Supplier:  Medchemexpress LLC HY128359100MG

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ACBI1 is a potent PROTAC degrader that cooperatively degrades SMARCA2, SMARCA4, and PBRM1, with DC50 values of 6, 11, and 32 nM respectively. It exhibits anti-proliferative activity and induces apoptosis. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase von Hippel-Lindau.

  • Potent and cooperative degrader of SMARCA2, SMARCA4, and PBRM1
  • Exhibits anti-proliferative activity in vitro
  • Induces apoptosis
  • Composed of a bromodomain ligand, a linker, and E3 ubiquitin ligase
  • Soluble in DMSO (≥ 100 mg/mL)
  • Suitable for in vivo applications with specific solvent systems

Catalog No. 50-003-39278


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