Acemetacin

Description

A potent inhibitor of COX-2 found to have anti-tumor activity in the colon | CAS: 53164-05-9 | C21H18ClNO6 | 415.826 g/mol

A potent inhibitor of COX-2 found to have anti-tumor activity in the colon

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 53164-05-9
• Molecular Formula: C21H18ClNO6
• Molecular Weight (g/mol): 415.826
• MDL Number: MFCD00151473
• InChI Key: FSQKKOOTNAMONP-UHFFFAOYSA-N
• Synonym: acemetacin, rantudil, emflex, acemetacinum, acemix, acemetacina, acemetacine, aximeixin, rheumibis, indomethacin carboxymethyl ester
• PubChem CID: 1981
• ChEBI: CHEBI:31162
• IUPAC Name: 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid
• SMILES: CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O

• Melting Point: 149°C to 153°C
• Color: Yellow
• Quantity: 10 g
• UN Number: UN2811
• Merck Index: 14,27
• Formula Weight: 415.83
• Physical Form: Powder
• Chemical Name or Material: Acemetacin

Safety and Handling

Hazard Category	H300+H310+H330
Hazard Statement	GHS H Statement H300-H310-H330 Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.
Precautionary Statement	P260-P262-P264b-P270-P271-P280-P284-P301+P310-P302+P350-P304+P340-P310-P330-P361-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	258-403-4
RTECSNumber	NL3521400
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only