Medchemexpress LLC Acesulfame (potassium) | 55589-62-3 | 99.4% | 10 G

Supplier:  Medchemexpress LLC HYD019510G

Acesulfame potassium is a synthetic sweetener that can affect cognitive function by altering neurometabolic functions. It can also suppress autophagic degradation of PD-L1 in cancer cells, which may be related to immune evasion. This product is suitable for research on neurological diseases, metabolic disorders, cancer, and immune evasion.

• Research applications include neurological diseases, metabolic disorders, cancer, and immune evasion.
• Upregulates PD-L1 protein levels in RIL-175 and SK-Hep1 cells.
• Increases granzyme B production in co-cultured T cells.
• Activates ERK1/2-mTORC1-ULK1 pathway to suppress autophagic degradation of PD-L1.
• Inhibits mitochondrial metabolism and impairs neuroprotective functions in SH-SY5Y cells.
• Affects body weight and gut microbiome composition in male CD-1 mice.
• Alters neurometabolic functions in C57BL/6J mice.

Catalog No. 50-004-09863