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Medchemexpress LLC Acetamide, N-[2-[[4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]-1,3,5-triazin-2-yl)amino]ethyl] | 2767424-13-3 | 98.0% | C21H23N5O2 | 10MG
SDP

Supplier:  Medchemexpress LLC HY13978110MG

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PD-L1-IN-1 is a small-molecule inhibitor of the PD-1/PD-L1 immune checkpoint intended for research use. It binds PD-L1, shows an IC50 of 115 nM, enhances IFN-γ release and peripheral blood mononuclear cell-mediated killing of PD-L1-expressing cancer cells, and induces apoptosis while showing low cytotoxicity in healthy cells.

  • Potent PD-L1 inhibition (IC50 115 nM).
  • Enhances IFN-γ release and immune cell-mediated tumor cell killing.
  • Induces apoptosis in PD-L1-expressing cancer cell lines.
  • Low cytotoxicity in noncancerous cells.
  • High solubility in DMSO for assay preparation.
  • Defined storage recommendations for powder and solutions.

Catalog No. 50-002-58601


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