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Medchemexpress LLC Acetamide, n-(4-azidobutyl)-thalidomide derivative | 2098488-36-7 | MFCD31560486 | 98.4% | 428.40 g/mol | C19H20N6O6 | 50 MG
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Supplier:  Medchemexpress LLC HY10361550MG

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Thalidomide-O-amido-C4-N3 is a thalidomide-derived E3 ligase (cereblon) ligand-linker conjugate containing an azide functional group for bioconjugation. It is used as a click-chemistry reagent and building block in targeted protein degradation (PROTAC) research. The compound has defined solubility profiles for in vitro and in vivo formulations and is supplied with storage recommendations for stability.

  • Contains an azide group for CuAAc and SPAAC click reactions.
  • Functions as a cereblon (CRBN) recruiter in PROTAC constructs.
  • High purity verified by LCMS (98.36%).
  • Good solubility in DMSO (≥ 41 mg/mL) and formulatable for in vivo use (≥ 2.5 mg/mL).
  • Storage recommendations: 4°C under nitrogen; in solvent, -80°C (6 months) or -20°C (1 month).

Catalog No. 50-002-44990


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