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Medchemexpress LLC Acetazolamide (sodium) | 1424-27-7 | 99.5% | 1 G
Supplier: Medchemexpress LLC HYB0782A1G
Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. It also inhibits hCA II with an IC50 of 130 nM. It exhibits diuretic, antihypertensive, and anti-gonococcal activities, and is intended for research use only.
- Inhibits carbonic anhydrase (CA) IX with an IC50 of 30 nM
- Inhibits carbonic anhydrase (CA) II with an IC50 of 130 nM
- Potentiates anti-tumor potential in neuroblastoma models
- Reduces expression of HIF1-α and CAIX in neuroblastoma xenograft
- Significantly reduces gonococcal load in infected mice
- Promotes apoptosis in Hep-2 cells
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