ABclonal Technology Acetyl-alpha Tubulin -K40

Supplier:  ABclonal Technology A2473820UL

This gene encodes alpha tubulin a key component of microtubules which are essential for various eukaryotic cell functions Microtubules are composed of alpha and beta tubulin dimers with gamma tubulin playing a role in microtubule assembly Alpha and beta tubulin genes are highly conserved across species while gamma tubulin is involved in nucleation This gene is one of three alpha-tubulin genes located on chromosome 12q and is similar to mouse and rat Tuba1 genes It is predominantly expressed in differentiated neurological cells Mutations in this gene cause lissencephaly type 3 (LIS3) a neurological disorder marked by microcephaly intellectual disability and early-onset epilepsy due to impaired neuronal migration Alternative splicing produces multiple transcript variants encoding distinct isoforms

Catalog No. 50-000-08389