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Enzo Life Sciences N-Acetyl-S-geranylgeranyl-L-cysteine (25mg). CAS: 139332-94-8
Supplier: Enzo Life Sciences BMLG2200025
AGGC specifically blocks methyl esterification of geranylgeranylated proteins such as Rab proteins. AGGC blocks receptor-mediated signal transduction in human neutrophils (IC50=4 µM). Induces insulin release from HIT-T15 cells by mimicking the action of Rab3A and inhibits β2-integrin-induced actin polymerization (IC50~45 nM) in neutrophils. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml). Long Term Storage: -20°C.
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