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Bachem Acetyl-(Nle4,Asp5,D-Phe7,Lys10)-cyclo-a-MSH (4-10) amide Acetate

Supplier: Bachem 4039778.0001

Acetyl-(Nle4,Asp5,D-Phe7,Lys10)-cyclo-a-MSH (4-10) amide Acetate, Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys-NH2), 121062-08-6, C50H69N15O9, Mr 1024.19, 1mg. Melanotan II, MTII, Bremelanotide amide, (Ac-Nle4, Asp5, DPhe7, Lys10)-Cyclo-a-MSH (4-10) amide. Melanotan II, a cyclic MSH analog, is a potent full agonist of the melanocortin-3 and melanocortin-4 receptors (MC3-R and MC4-R). Intracerebroventricular administration of MTII inhibited feeding in four different mouse models of hyperphagia. MTII is a valuable tool for the study of the agouti obesity syndrome and of the role of melanocortinergic neurons in feeding.
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